Skip to main content

Table 2 Sensitivity analysis variables and outcomes

From: Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya

Variable Baseline
value
Revised
values
in
sensitivity
analysis
Justification Impact on
cost per child
per year
(Baseline:
US$1.88)
Impact on Cost effectiveness
      Cost per case of anaemia averted
(Baseline: US$ 29.84)
Cost per case of parasitaemia averted
(Baseline: US$ 5.36)
SP Price US$ 0.08 per dose 200% Drug price and brand are liable to change over time and across settings US$ 1.61
US$ 2.30
US$ 25.56
US$ 36.51
US$ 4.59
US$ 6.55
AQ Price US$ 0.12 per dose 50%
200%
As above US$ 1.55
US$ 2.54
US$ 24.60
US$ 40.32
US$ 4.2
US$ 7.24
Drug Wastage 10% 0%
20%
Variations in expert opinion & literature US$ 1.80
US$ 1.95
US$ 28.57
US$ 30.95
US$ 5.13
US$ 5.56
Exchange rate US$ 1= Kes 67.81 US$ 1 = Kes 74.5
US$ 1 = Kes 67.1
Rate over 2006, and highest and lowest 2006 rates US$ 1.78
US$ 2.13
US$ 28.25
US$ 33.81
US$ 5.07
US$ 6.07
Discount rate 5% 3% – 7% 5% is standard practice, with 3–7% used occasionally Negligible change Negligible change Negligible change
Change in wages 2006 + 20% Salaries levels liable to change. 20% is a realistic change in next few years US$ 1.96 US$ 31.11 US$ 5.58
Effectiveness: reduction in % anaemia 50% 10%
30%
Effectiveness may vary in different settings and when implemented outside of an efficacy trial Not applicable US$ 149.21
US$ 49.74
Not applicable
Effectiveness: reduction in % parasitaemia 88% 40%
60%
As above Not applicable Not applicable US$ 11.84
US$ 7.89
Baseline % anaemia in Reduction in % parasitaemia 12.6% 30%
50%
Background nutritional levels vary between settings Not applicable US$ 12.53
US$ 7.52
Not applicable
Frequency of delivery Three times a year Twice a year Yearly distribution as in efficacy trial versus seasonal distribution US$ 1.42 Not applicable Not applicable
Drug Choice SP/AQ SP alone
DP
Current drug regime versus alternative drug regime currently under investigation US$ 1.19.
US$ 4.50
Not applicable Not applicable