Figure 3

Depiction of the whole system model of the haematocrit layer. a) Schema of the culture system according to the model used to tackle P trials. HLD indicates haematocrit layer depth, L stands for the separation between walls of the culturing device and L _EXC represents the extent of the exclusion region, where the spread of the infection is hindered. The shaded subregion (1) indicates the fraction of the haematocrit layer where the rate of infection spreading is high. b) Schema of the culture system according to the model used to tackle B and W trials. HLD indicates the haematocrit layer depth, D stands for the diameter of the haematocrit layer and h represents the region where the spread of the infection is not hindered. The shaded subregion (1) indicates the fraction of the haematocrit layer where the rate of infection spreading is high. c) Schaema of the model to tackle all the geometric effects simultaneously. The propagation of the infection is hindered both by the walls of the culturing device and by diffusive limitations. The shaded subregion (1) indicates the fraction of the haematocrit layer where the rate of infection spread is high.