Table 2 Initial parameter estimates used in the model

Costs:

ACT

$1.8 (adult dose)

Uganda MoH

Antibiotic

$0.4 (adult dose)

Primary data – Joint Medical Store

pLDH RDT

$.51

Manufacturer

HRP2 RDT

$.55

Manufacturer

Harm of treatment with ACT (or antibiotic)

Every 200/2000 ACT doses currently used result in the loss of one statistical life

[11]

Inpatient care severe malaria

$12

Primary data, Kisiizi Hospital

Inpatient care severe NMFI

$20

Accuracies:

pLDH sensitivity

77.1%

Primary trial data

pLDH specificity

98.4%

Primary trial data

HRP2 sensitivity

98.8%

Primary trial data

HRP2 specificity

87.0%

Primary trial data

Illness progression probabilities:

Adherence

Full adherence -100%

Variable in model

Year of Life Lost (YLL)

$150, $840

[29-31]