Table 1 Clinical features at baseline of children suffering from acute uncomplicated malaria by body weight group (ITT population)

Number enrolled and treated (ITT)

50

37

16

103

Sex (M: F)

21:29

21:16

8:8

50:53

Age (years)

   Mean ± SD

1.3 ± 0.56

3.4 ± 1.3

6.5 ± 1.76

2.8 ± 2.13

   Range

0.2 – 3.1

0.9 – 6.8

4.0 – 9.9

0.2 – 9.9

Non-Immune (n)

15

-

-

15

Weight (kg)

   Mean ± SD

8.0 ± 1.05

12.3 ± 1.52

18.7 ± 1.87

11.2 ± 4.0

   Range

5.1 – 9.6

10 – 14.5

15.5 – 22

5.1 – 22

Parasite density (/μL)

   Mean ± SD

21,286 ± 19,900

32,668 ± 27,400

27,656 ± 26,074

26,364 ± 24,135

   Range

2,927–95,546

2,112–106,425

2,332–104,919

2,112–106,426

Temperature (°C)

   Mean ± SD

38.9 ± 0.80

38.8 ± 0.86

39.0 ± 0.64

38.9 ± 0.80

   Range

37.6 – 40.8

37.6 – 40.3

37.9 – 39.8

37.6 – 40.8

Haemoglobin (g/L)

Mean ± SD

90.2 ± 14.73

92.7 ± 16.41

103.4 ± 15.87

93.3 ± 16.04

Haematocrit (%)

Mean ± SD

27.9 ± 4.12

28.6 ± 4.17

30.9 ± 4.77

28.6 ± 4.33