| | | |
P. vivax dhfr polymorphism
|
P. vivax dhps polymorphism
|
|---|
|
Sampling site
|
No. of isolates
|
No. of mutant isolates (%)
|
Amino-acid residue
|
No. of mutant isolates (%)
|
Amino-acid residue
|
|---|
| | | | |
P21S
|
P33L
|
C49R
|
S58R
|
S117N
|
N130K
| |
A383G
|
C422R
|
|---|
|
South
|
Ejeda
|
11
|
2 (18)
|
-
|
1
|
-
|
1
|
1
|
-
|
0 (0)
|
0
|
0
|
| |
Ihosy
|
1
|
1 (100)
|
-
|
-
|
-
|
-
|
1
|
-
|
0 (0)
|
0
|
0
|
|
West
|
Miandrivazo
|
60
|
50 (83)
|
1
|
1
|
-
|
43
|
47
|
44
|
2 (3)
|
1
|
1
|
| |
Maevatanana
|
22
|
14 (64)
|
-
|
2
|
5
|
12
|
12
|
-
|
8 (36)
|
8
|
0
|
|
Central Highlands
|
Tdd
|
59
|
42 (71)
|
1
|
4
|
-
|
33
|
37
|
6
|
11 (19)
|
11
|
0
|
| |
Moramanga
|
5
|
3 (60)
|
-
|
1
|
-
|
2
|
2
|
-
|
3 (60)
|
3
|
0
|
|
East
|
Farafangana
|
1
|
1 (100)
|
-
|
-
|
-
|
1
|
1
|
-
|
1 (100)
|
1
|
0
|
|
Total
| |
159
|
113 (71)
|
2 (1.3)
|
9 (5.7)
|
5 (3.1)
|
92 (57.9)
|
101 (63.5)
|
50 (31.4)
|
25 (16)
|
24 (15)
|
1 (0.6)
|
- Residues displaying new mutations are indicated in bold typeface
- Tdd: Tsiroanomandidy
