Figure 1
From: Immunologic activation of human syncytiotrophoblast by Plasmodium falciparum
Activation of JNK following iRBCST binding. BeWoST cells were co-cultured with iRBCST or uRBC for the indicated time course or left unstimulated (0). Panel A represents a western blot analysis of cellular proteins from ST cells following stimulation. Densitometry analysis of the western blot results from two experiments was performed. Figure B shows specific enhanced phosphorylation (~2.5 fold) of JNK1 (p-JNK1) after 30 minutes of co-culture with iRBCST. Co-culture with uRBCs led to a slight increased phosphorylation (< 1.5 fold increase over unstimulated) after 15 minutes. Data shown represent mean ± SD fold increase relative to unstimulated cells from two separate experiments.