Figure 2
From: Immunologic activation of human syncytiotrophoblast by Plasmodium falciparum
Gene expression changes in ST stimulated with iRBCST. Primary ST was stimulated with either uRBC or iRBCST. RNA was extracted and gene expression changes assayed by real time PCR. This treatment led to the marginal, but not statistically significant, upregulation of both TGF-β and IL-8/CXCL8 which showed more than two-fold increases in their mRNA expression at two hours and 12 hours, respectively. TNF, IL-10 and MIF mRNA did not change considerably with this treatment. Dotted line shows gene expression of uRBC-stimulated cells. Mean ± SD from three placentas is shown.