Figure 2

Gene content and organization of the segmental duplicon SD1. (A) Example of a typical SD1 containing six complete genes. Genes encoding PEXEL-containing proteins are depicted in black. A red arrow indicates the position of the hypervariable loop in pfmc2tm. (B) The SD1 exists in eight copies in the 3D7 genome with a slight variation in respect to the rif gene. Homologous rif copies, with > 95% sequence homology, in between the SD1s are shown with the same color. Crosses indicate breakpoints of each SD1.