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Table 1 Baseline characteristics of study sites and patients at enrolment

From: The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New Guinea

  Study site
Characteristics Karimui area (Simbu Province) South Wosera (East Sepik Province)
Study sites n = 80 n = 94
Endemicity* mesoendemic mesoendemic
Transmission intensity§ moderate high
Patients   
Weight (mean (95% CI), kg) 13.8 (12.9–14.6) 14.4 (13.8–15.1)
Age (mean (95% CI), yrs) 4.0 (3.7–4.4) 4.5 (4.2–4.8)
Sex: female/n (%) 43/97 (44.3) 59/112 (52.7)
Temperature (mean (95% CI),°C) 38.7 (38.5–38.9) 38.7 (38.4–39.0)
Haemoglobin (mean (95% CI), g/dl) 9.0 (8.6–9.5) 9.0 (8.7–9.3)
Parasite density (geometric mean (range), per μl) 21937 (1120–329400) 40526 (280–774400)
Multiplicity of infection (= MOI) (mean (95% CI)) 1.48 (1.34–1.63) 1.73 (1.59–1.88)
Spleen rate# (% (95% CI)) 43.3 (33.3–53.7) 50.9 (41.3–60.5)
  1. * Assessed by concomitant cross-sectional surveys in both study areas which showed P. falciparum prevalence rates of 11–50% in children aged 2–9 years (WHO, 2003); § Müller et al., 2003; # proportion of children with enlarged spleen