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Table 1 Baseline Parameter Values

From: Clinically immune hosts as a refuge for drug-sensitive malaria parasites

Acquisition of clinical immunity

θ-1

10 years

Loss of clinical immunity

γ-1

2 years

Fraction of new infections that are treated and cleared

ξ1

0.3

 

ξ2

0.01

Rate clinical symptoms arise (σ i ) times Fraction treated (f i ) equals rate existing infections are cleared by drugs (ρ i )

σ1f1 = ρ1

0.025(0.2) = 1/200

 

σ2f2 = ρ2

0.01(0.2) = 1/500

Disease induced death rate

m

180/100000/year

Human feeding rate

α

0.3

Infectivity rate

b

0.8

Mosquito death rate

g

1/10

Number of days required for sporogony

n

10

Recovery rate

r w

1/(165/b)

 

r x

r w (fitness cost)