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Figure 2 | Malaria Journal

Figure 2

From: The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites

Figure 2

P. chabaudi clone CB induces more anaemia than clone AS in BALB/c mice. a) Drop in the number of circulating RBCs; b) drop in the Hb level in the blood over the course of the primary infection; c) Number of circulating parasites and d) % of pRBC over the same time scale in AS-infected mice (black circle), CB-infected mice (open circle) and naive control animals (-). For each day the circles in a) to d) represent the average and the error bars the standard error of the mean (SEM) of 5 animals from experiment 2. e) and f) residual number of circulating RBCs after experiment and clone have been taken into consideration plotted against peak percentage parasitemia (e) or peak number of pRBC (f) for all three experiments. Each symbol represents the values for a single mouse infected with clone AS (black circle) or clone CB (open circle). The solid lines represent the best fit linear regression line in each case, and the dashed lines highlight the residual anaemia observed once the data is normalized for experimental and clonal variation in the magnitude of RBC loss (ANOVA model "RBC loss = experiment+clone").

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