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Table 2 Comparison of predicted means of least squares analyses of biomarkers by disease category

From: Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India

  

CATEGORY

BIOMARKER

OVERALL P-VALUE

HC VS. MM

HC VS. CMS

HC VS. CMNS

MM VS. CMS

MM VS. CMNS

CMS VS. CMNS

IL-1RA

0.0002

p < .05

p < .0045

p < .05

p < .05

NS

NS

IL-8

0.0003

p < .05

p < .0045

NS

p < .05

NS

NS

IL-10

<.0001

p < .0045

p < .0045

NS

NS

NS

NS

STNF-R1

0.0005

NS

p < .05

p < .0045

p < .05

p < .05

NS

STNF-R2

0.0002

p < .05

p < .0045

p < .0045

NS

p < .05

p < .05

VEGF

<.0001

NS

NS

p < .0045

NS

p < .0045

p < .0045

IP-10

0.0005

NS

p < .0045

p < .0045

p < .05

p < .05

NS

MIP-1β

0.0001

p < .05

p < .0045

NS

NS

NS

NS

PDGFbb

0.0056

NS

p < .05

p < .0045

NS

NS

NS

SFas

< .0001

NS

p < .05

p < .0045

p < .05

p < .0045

p < .05

Fas-L

0.0174

p < .05

p < .05

p < .05

NS

NS

NS

  1. Significant differences in biomarkers in relation to disease severity determined by multivariate analyses (Comparison of Least Squares (Predicted) with Bonferonni correction) after modeling and controlling for covariates (age, sex, and parasitaemia).