Table 1 Antifolate resistance multiple mutants in the vicinity of Macha, 1988 – 2006.
From: Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia
| Mutant | ||||
|---|---|---|---|---|
| Survey Year | DHFR triple | DHPS double | DHFR/DHPS quintuple | N |
| 1988 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 110 |
| 2000 | 0 (0.0%) | 1 (2.0%) | 0 (0.0%) | 49 |
| 2003 | 10 (40.0%) | 2 (8.0%) | 1 (4.0%) | 25 |
| 2006 | 38 (41.3%) | 10 (16.1%) | 4 (6.5%) | 95 |