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Table 2 The number of targets suggested for further study using experimental structural elucidation techniques in each priority category (PC, ranked 1 – 6) after the relevant elimination step.

From: A structural annotation resource for the selection of putative target proteins in the malaria parasite

Priority Class (PC)

PDB E-value range

Nr of proteins

Tm + disorder

CC+LC+SP

a

b

PC1

No PDB matches

139

11

8

1

7

PC2

E-value > 10

174

15

11

3

8

PC3

10 >= E-value > 5

352

34

31

9

22

PC4

5 >= E-value > 3

332

35

19

5

14

PC5

3 >= E-value > 1

810

88

51

12

39

PC6

1 >= E-value > 0.5

529

60

58

10

48

  1. Tm+disorder refers to the amount of proteins in each group after the transmembrane and disorder filtering step. CC+LC+SP refers to the proteins in each group after coiled-coils, low complexity and signal peptide filtering step. Group a indicates proteins containing a Pfam functional domain. Group b indicates proteins without a Pfam functional domain.