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Table 2 The number of targets suggested for further study using experimental structural elucidation techniques in each priority category (PC, ranked 1 – 6) after the relevant elimination step.

From: A structural annotation resource for the selection of putative target proteins in the malaria parasite

Priority Class (PC) PDB E-value range Nr of proteins Tm + disorder CC+LC+SP a b
PC1 No PDB matches 139 11 8 1 7
PC2 E-value > 10 174 15 11 3 8
PC3 10 >= E-value > 5 352 34 31 9 22
PC4 5 >= E-value > 3 332 35 19 5 14
PC5 3 >= E-value > 1 810 88 51 12 39
PC6 1 >= E-value > 0.5 529 60 58 10 48
  1. Tm+disorder refers to the amount of proteins in each group after the transmembrane and disorder filtering step. CC+LC+SP refers to the proteins in each group after coiled-coils, low complexity and signal peptide filtering step. Group a indicates proteins containing a Pfam functional domain. Group b indicates proteins without a Pfam functional domain.