Figure 7From: Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium bergheiDetermination of pbmrp transcript levels in sensitive and drug resistant P. berghei parasites. (A) Representative results of an RPA analysis using total RNA dilutions from the drug sensitive N clone or the CQ selected RC line showing protected fragments with the βtub or pbmrp riboprobes. βtub was included as a normalizing control. (B) Densitometric analysis of pbmrp expression. Densities of the normalized pbmrp signals were subsequently normalized to the drug sensitive N-clone to estimate the relative mRNA expression levels in RC. The horizontal line represents mean relative expression of four experiments.Back to article page