Figure 4

Parasitaemia and survival of Plasmodium berghei -infected mice. A: Original histograms of parasitaemia-dependent Syto16 fluorescence in untreated animals (upper panels) and animals treated from day 8 until day 20 with 5 mg/kg b.w. of azathioprine s.c. (lower panels) 10 (left panels) and 20 (right panels) days after infection with P. berghei. B: Arithmetic means ± SEM of parasitaemia in mice without treatment (open circles, n = 12) or with 5 mg/kg b.w. of azathioprine s.c. (closed circles, n = 9) as a function of days after infection with P. berghei. * indicates significant difference (p ≤ 0.05; t-test) from the untreated animals. C: Survival of mice without treatment (open circles) or with 5 mg/kg b.w. of azathioprine s.c. (closed squares) as a function of days after infection with P. berghei.