Figure 1

DB75 inhibition of P. falciparum. The percent inhibition of parasite growth was measured with tritiated hypoxanthine for asynchronous parasites exposed to drug for 42 hours (grey line, open circle); synchronized ring-stage parasites exposed to drug for 36 hours (black line, closed square); synchronized rings-stage parasites exposed to drug for 96 hours (black line, open square); and synchronized trophozoite-stage parasites exposed to drug for 36 hours (black line, closed triangle).