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Table 2 In vivo outcome measures

From: Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia

Study

Number of patients

Treatment outcome (n. %)

 

Included

Drop out*

Analysed

ACPR

LTF

LPF

LCF

AL2002†

55

10(4)

45

32(71.1)

13(28.9)

2(4.4)

11(24.5)

AL2003†

80

6(3)

74

64(86.5)

10(13.5)

6(8.1)

4(5.4)

AM2003‡

55

3(0)

52

48(92.3)

4(7.7)

3(5.7)

1(2)

AM2004‡

85

4(1)

81

75(92.6)

6(7.4)

0(0)

6(7.4)

  1. ACPR. Adequate Clinical and Parasitological Response; LTF. Late Treatment Failure;
  2. LCF. Late Clinical Failure; LPF. Late Parasitological Failure; LTF = LCF + LPF.
  3. *Number between parenthesis indicates the number Plasmodium vivax infections
  4. †Artemether 20 mg/kg and lumefantrine 120 mg/kg
  5. ‡Artesunate 12 mg/kg and mefloquine 25 mg/kg
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Malaria Journal

ISSN: 1475-2875

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