Impact of child malnutrition on the specific anti-Plasmodium falciparum antibody response

Malaria Journal

Table 2 Specific IgG immune responders and geometric mean of parasite density in rural preschool Senegalese children

	n	Responders ^a (%)	P ^b	n	Geometric mean of parasite density^c [95% CI]	P ^d
Groups of children
Malnourished children	161	118 (73.3)	0.001	140	3.87 [2.42–6.21]	0.34
Paired controls	161	140 (87.0)		140	5.27 [3.38–8.23]
Stunted children	142	104 (73.2)	0.001	123	4.57 [2.69–7.75]	0.56
Paired controls	142	125 (88.0)		123	5.62 [3.48–9.08]
Wasted children	19	14 (73.7)	0.65	17	1.18 [0.83–1.66]	0.13
Paired controls	19	15 (78.9)		17	3.34 [0.91–12.23]
Stunted children (-2.5<HAZ<-2.0)	84	62 (73.8)	0.01	72	6.44 [3.01–13.80]	0.89
Paired controls	84	74 (88.1)		72	6.28 [3.23–12.22]
Stunted children (HAZ≤-2.5)	58	42 (72.4)	0.03	51	2.71 [1.35–5.43]	0.19
Paired controls	58	51 (87.9)		51	4.93 [2.43–10.02]

^a Number of IgG anti-schizont immune responders
^b The prevalence of immune responders between groups was compared using the Mac Nemar test.
^c Assessment of parasitaemia missing for 21 pairs of children.
^d Geometric means between groups were compared using paired t-test.

ISSN: 1475-2875