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Table 2 Time course of OHCT action.

From: Antimalarial activity of a cis-terpenone

Time (min)

Parasitaemia (%)

30 min

8.6

60

8.5

120

8.6

240

8.1

360

6

480

4.7

Vehicle (0.1% DMSO)

8.9

Media

9.1

  1. The P. falciparum clone Dd2 (CQR) was treated with 0.5 μM OHCT for the times shown. Parasite viability was measured by the lactate dehydrogenase assay.