Figure 1

A: Thoracic CT scan. Multiple confluent ground glass-infiltrates in both lungs due to Aspergillus fumigatus. B and C: Bronchoscopic findings. B: Sharply circumscribed lesion of the carina tracheae of the upper left lobe, extending into the upper lobe bronchus. C: Extensive necrosis of the bronchial wall extending into the periphery up to segment 2 of the upper right lobe. D-G: Histological findings of the transbronchial biopsy. D: Overview of the biopsy specimen, HE stain, primary magnification × 5. The black box indicates the area shown in E, primary magnification × 20: PAS staining showing extensive invasive growth of hyphae into the bronchial wall (black arrows). F: Mycelia of Aspergillus fumigatus with dichotomy branching (black arrows) with inflammatory infiltrates and necrosis (white arrows), PAS stain, primary magnification × 10. G: Extensive fungal growth with partially septated hyphae (black arrows), PAS stain, primary magnification × 20.