Table 2 Variations of fever, parasitaemia and haemoglobin over the time in the studies in Boende and Kabal
|
Characteristics N | Boende | Kabalo | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
SP 107 |
AQ 106 |
AS+SP 91 |
AS+AQ 90 | p |
SP 60 |
AS+SP 62 |
AS+AQ 58 | p | |
| Proportion febrile d1 (%) |
20/106 (18.7) |
9/105 (8.5) |
8/91 (8.8) |
5/89 (5.6) | 0.01 |
9/59 (15.3) |
5/62 (8.1) |
5/58 (8.6) | 0.37 |
| Proportion febrile d2 (%) |
21/103 (20.4) |
3/105 (2.8) |
3/91 (3.3) |
2/87 (2.2) | <0.001 |
13/58 (22.4) |
1/62 (1.6) |
1/58 (1.7) | <0.001 |
| Proportion parasitaemic d2(%) |
84/103 (81.5) |
90/105 (85.7) |
60/91 (65.9) |
56/87 (64.4) | <0.001 |
35/58 (60.3) |
8/62 (12.9) |
9/58 (15.5) | <0.001 |
| Proportion parasitaemic d7(%) |
12/97 (11.4) |
6/98 (6.1) |
25/89 (28.1) |
25/85 (29.4) | <0.001 |
5/51 (9.8) |
7/60 (11.7) |
1/54 (1.8) | 0.12 |
|
Hb d0 median [range] |
9.7 [6.0–12.7] |
9.7 [5.0–11.7] |
9.7 [6.7–12.7] |
9.7 [6.7–12.7] |
10.7 [6.7–12.7] |
10.7 [6.7–14.0] |
10.7 [6.0–14.0] | ||
| Anaemia* d0 (%) |
100 (93.4) |
102 (96.2) |
83 (91.2) |
83 (92.2) | 0.51 |
31 (51.7) |
39 (62.9) |
36 (62.1) | 0.38 |
|
Hb d28 median [range] |
10.7 [6.7–12.7] |
10.7 [6.7–12.7] |
10.7 [7.0–12.7] |
10.7 [7.3–12.7] |
11.7 [10.7–12.7] |
11.7 [9.7–12.7] |
11.7 [9.7–14.0] | ||