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Table 4 Predictors of first-line therapy prescription and co-prescription of concomitant antibiotics1,2

From: Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy

 

Prescription of first-line therapy (ART-AQ)

Antibiotic use

 

Adjusted odds ratio

[95% CI]

p-value

Adjusted odds ratio

[95% CI]

p-value

Age group

<5

1.0

 

1.0

 

5–12

3.6 [2.6–4.9]

<0.001

-

-

13–59

2.5 [2.0–3.1]

<0.001

0.53 [0.44–0.64]

<0.001

≥60

2.6 [1.8–3.9]

<0.001

0.55 [0.37–0.83]

0.004

Facility type

Non-government

1.0

 

-

-

Government

6.3 [3.6–11.1]

<0.001

-

-

Mode of diagnosis

Presumptive

1.0

 

1.0

 

Laboratory confirmed

9.7 [5.2–18.2]

<0.001

0.68 [0.41–1.1]

0.13

Anti-malarial treatment prescribed

Combination therapy (ART-AQ)

-

-

1.0

 

Combination therapy (Other ACT)

-

-

-

-

Monotherapy (Artemisinin based)

-

-

1.2 [0.97–1.4]

0.11

Monotherapy (Non-artemisinin)

-

-

1.4 [1.1–1.9]

0.02

  1. 1 Gender was not significant in either of the final models
  2. 2 N = 2,535 for both models. Patients with unknown age (n = 31) and/or unknown mode of diagnosis (n = 272) were excluded.