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Table 4 Predictors of first-line therapy prescription and co-prescription of concomitant antibiotics1,2

From: Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy

  Prescription of first-line therapy (ART-AQ) Antibiotic use
  Adjusted odds ratio [95% CI] p-value Adjusted odds ratio [95% CI] p-value
Age group
<5 1.0   1.0  
5–12 3.6 [2.6–4.9] <0.001 - -
13–59 2.5 [2.0–3.1] <0.001 0.53 [0.44–0.64] <0.001
≥60 2.6 [1.8–3.9] <0.001 0.55 [0.37–0.83] 0.004
Facility type
Non-government 1.0   - -
Government 6.3 [3.6–11.1] <0.001 - -
Mode of diagnosis
Presumptive 1.0   1.0  
Laboratory confirmed 9.7 [5.2–18.2] <0.001 0.68 [0.41–1.1] 0.13
Anti-malarial treatment prescribed
Combination therapy (ART-AQ) - - 1.0  
Combination therapy (Other ACT) - - - -
Monotherapy (Artemisinin based) - - 1.2 [0.97–1.4] 0.11
Monotherapy (Non-artemisinin) - - 1.4 [1.1–1.9] 0.02
  1. 1 Gender was not significant in either of the final models
  2. 2 N = 2,535 for both models. Patients with unknown age (n = 31) and/or unknown mode of diagnosis (n = 272) were excluded.