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Table 2 Distribution of dhfr and dhps polymorphisms of P. vivax in 143 samples collected in 2001 to 2006 from south-eastern of Iran

From: Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East

pvdhps/pvdhfr Haplotype

2001

2003

2004

2005

2006

n = 143

n = 36

n = 16

n = 33

n = 29

n = 29

AAIPFSTSI

30 (83.33)

9 (56.25%)

19 (57.58%)

14 (48.28%)

13 (44.83%)

AAIPFSTNI

2 (5.56%)

5 (31.25%)

6 (18.18%)

8 (27.59%)

5 (17.24%)

AAIPFRTSI

3 (8.33%)

1 (6.25%)

3 (9.09%)

4 (13.79%)

2 (6.89%)

AAIPFRTNI

1 (2.78%)

1 (6.25%)

4 (12.12%)

3 (10.34%)

8 (27.59%)

AAIPLSTSI

-

-

1 (3.03%)

-

-

AAIPLRTSI

-

-

-

-

1 (3.45%)