Table 1 Baseline characteristics. Median (range) or number of patients (%).

Artesunate PK group

N = 35

N = 35

Age (months)

37 (7 – 59)

32 (11 – 58)

Weight (kg)

14 (7 – 17)

12 (7.5 – 19)

Sex (n (%) males)

25 (71)

15 (43)

Temperature (°C)

39.0 (37.5 – 40.6)

38.7 (37.5 – 40.1)

Gametocytaemia

(n (%) with gametocytes)

6 (17)

3 (9)

Hepatomegaly (n (%))

0 (0)

1 (3)

Splenomegaly (n (%))

1 (3)

1 (3)

Parasite count (/μL)

30,000 (2000 – 162,000)

29,000 (2000 – 393,000)

Amodiaquine PK group

N = 35

N = 35

Age (months)

26 (12 – 59)

29 (7 – 58)

Weight (kg)

12 (7 – 31)

12 (6 – 19)

Sex (n (%) males)

16 (46)

20 (57)

Temperature (°C)

38.4 (37.5 – 40.2)

38.4 (37.5 – 40.8)

Gametocytaemia

(n (%) with gametocytes)

1 (3)

7 (20)

Hepatomegaly (n (%))

1 (3)

0 (0)

Splenomegaly (n (%))

1 (3)

2 (6)

Parasite count (/μL)

29,600 (1000 – 170,000)

27,000 (1000 – 468,000)