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Table 5 Haemoglobin and haematocrit values and changes between Day 0–14, and Day 0–28 (AS&AQ and comparators)

From: Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

Haemoglobin N Day 0 Day 7 Paired relative difference Paired difference t-value P-value
    mean sd Mean sd % lower 95%CI upper 95%CI mean sd   
Ndiaye ASAQ 766 10.1 2.29 9.6 2.02 -5% -3% -7% -0.50 1.24 -11.07 0.000
  AL 482 9.9 2.26 9.7 1.92 -2% 1% -4% -0.18 1.40 -2.89 0.004
Epicentre AS+AQ 249 10.3 1.76 9.8 1.74 -4% -1% -7% -0.42 1.19 -5.50 0.000
  AS+SP 248 10.2 1.88 9.7 1.66 -5% -2% -8% -0.51 1.20 -6.71 0.000
Haematocrit N Day 0 Day 7 Paired relative difference Paired difference t-value P-value
    mean sd Mean sd % lower 95%CI upper 95%CI mean sd   
Sirima AS+AQ 136 25.5 4.93 27.4 4.57 7% 4% 10% 1.87 3.75 5.83 0.000
  ASAQ 149 25.8 4.52 27.5 4.25 6% 4% 9% 1.64 3.12 6.40 0.000
Haematocrit N Day 0 Day 14 Paired relative difference Paired difference t-value P-value
    mean sd Mean sd % lower 95%CI upper 95%CI mean sd   
Karema AQ+SP 251 31.5 5.35 34.49 3.70 9% 8% 11% 2.95 4.95 9.44 0.000
  AS+AQ 247 31.0 5.49 33.99 3.66 10% 8% 11% 3.02 4.88 9.72 0.000
  DP 247 31.5 4.91 33.43 3.62 6% 4% 8% 1.90 5.24 5.70 0.000
Haemoglobin N Day 0 Day 28 Paired relative difference Paired difference t-value P-value
    mean sd mean sd % lower 95%CI upper 95%CI mean sd   
Ndiaye ASAQ 762 10.1 2.31 11.04 1.76 9% 7% 11% 0.96 1.74 15.48 0.000
  AL 471 9.96 2.26 10.93 1.59 10% 7% 12% 0.97 1.69 12.52 0.000
Epicentre AS+AQ 798 9.60 1.93 10.68 1.59 11% 9% 13% 1.08 1.68 18.18 0.000
  AS+SP 801 9.54 1.94 10.64 1.50 12% 10% 13% 1.10 1.66 18.77 0.000
Haematocrit N Day 0 Day 28 Paired relative difference Paired difference t-value P-value
    mean sd mean sd % lower 95%CI upper 95%CI mean Sd   
Sirima AS+AQ 259 26.7 6.00 31.38 4.50 18% 16% 20% 4.70 5.85 12.92 0.000
  ASAQ 258 26.7 5.59 31.33 5.02 17% 15% 20% 4.66 5.78 12.94 0.000
  1. Note. SD: standard deviation; CI: confidence interval