Skip to main content

Table 3 Descriptive statistics of the accuracy of procalcitonin (PCT) as a diagnostic tool for severe Plasmodium falciparum disease using various cut-off points.

From: Procalcitonin as a biomarker for severe Plasmodium falciparum disease: a critical appraisal of a semi-quantitative point-of-care test in a cohort of travellers with imported malaria

 

PCT cut-off point

P. falciparum species only (n = 71)

0,5 ng/ml

2,0 ng/mL

10,0 ng/mL

Sensitivity

1,00 [n.a.]

1,00 [n.a.]

0,67 [0,56-0,78]

Specificity

0,35 [0,24-0,46]

0,60 [0,49-0,71]

0,94 [0,88-1,00]

Positive predictive value

0,13 [0,05-0,21]

0,19 [0,10-0,28]

0,50 [0,38-0,62]

Negative predictive value

1,00 [n.a.]

1,00 [n.a.]

0,97 [0,93-1,00]

All plasmodium species (n = 100)

0,5 ng/ml

2,0 ng/mL

10,0 ng/mL

Sensitivity

1,00 [n.a.]

1,00 [n.a.]

0,67 [0,58-0,76]

Specificity

0,29 [0,20-0,38]

0,51 [0,41-0,61]

0,94 [0,83-0,95]

Positive predictive value

0,08 [0,03-0,13]

0,19 [0,06-0,18]

0,50 [0,20-0,38]

Negative predictive value

1,00 [n.a.]

1,00 [n.a.]

0,97 [0,95-1,00]

  1. Data is shown as proportion [95% confidence interval].