Table 3 Proportion of children with worse performance on day 7 and day 28 compared to day 0, after treatment with AS7 or MAS7 for P. falciparum, and in the non febrile controls.
Day 7 - Day 0 | |||||
|---|---|---|---|---|---|
Neurological Test Component | Result compared to previous test | AS7 N = 39 | MAS7 N = 39 | Controls non febrile N = 35 | P* 2 × 2 a 2 × 2 b |
Box | Worse | 11.6 (5) | 16.3 (7) | 11.4 (4) | 0.757 0.455 |
Cube | Worse | 14.0 (6) | 16.3 (7) | 31.4 (11) | 1.000 0.186 |
Ring | Worse | 11.6 (5) | 11.6 (5) | 11.4 (4) | 1.000 0.285 |
Coin | Worse | 4.7 (2) | 2.3 (1) | 2.9 (1) | 1.000 0.178 |
Behaviour | Worse | 11.6 (5) | 14.0 (6) | 31.4 (11) | 1.000 < 0.001 |
Tone | Decreased | 41.9 (18) | 40.5 (17) | 8.8 (3) | 1.000 0.026 |
Day 28 - Day 0 | |||||
Box | Worse | 5.1 (2) | 7.7 (3) | 9.7 (3) | 1.000 0.686 |
Cube | Worse | 15.4 (6) | 20.8 (8) | 16.1 (5) | 0.769 1.000 |
Ring | Worse | 5.1 (2) | 7.7 (3) | 25.8 (8) | 1.000 0.009 |
Coin | Worse | 5.1 (2) | 5.1 (2) | 9.7 (3) | 1.000 0.403 |
Behaviour | Worse | 15.4 (6) | 10.3 (4) | 45.2 (14) | 0.737 0.001 |
Tone | Decreased | 51.3 (20) | 44.7 (17) | 19.4 (6) | 0.650 0.009 |