Table 4 Proportion of children with worse performance on day 9, 10 and 14 compared to day 7, in children with P. falciparum treated with AS7 or MAS7.
Day 9 - Day 7 | ||||
|---|---|---|---|---|
Neurological Test Component | Result compared to previous test | AS7 N = 39 | MAS7 N = 39 | P* |
Box | Worse | 17.9 (7) | 20.5 (8) | 1.000 |
Cube | Worse | 15.4 (6) | 28.2 (11) | 0.272 |
Ring | Worse | 12.8 (5) | 20.5 (8) | 0.545 |
Coin | Worse | 12.8 (5) | 12.8 (5) | 1.000 |
Behaviour | Worse | 33.3 (13) | 30.8 (12) | 1.000 |
Tone | Decreased | 46.2 (18) | 53.8 (21^) | 0.651 |
Day 10 - Day 7 | ||||
AS7 N = 39 | MAS7 N = 39 | P* | ||
Box | Worse | 12.8 (5) | 15.4 (6) | 1.000 |
Cube | Worse | 23.1 (9) | 33.3 (13) | 0.457 |
Ring | Worse | 5.1 (2) | 20.5 (8) | 0.087 |
Coin | Worse | 7.7 (3) | 12.8 (5) | 0.711 |
Behaviour | Worse | 25.6 (10) | 30.8 (12) | 0.802 |
Tone | Decreased | 38.5 (15) | 50 (19^) | 0.363 |
Day 14 - Day 7 | ||||
AS7 N = 38 | MAS7 N = 38 | P* | ||
Box | Worse | 15.8 (6) | 21.1 (8) | 0.768 |
Cube | Worse | 23.7 (9) | 28.9 (11) | 0.795 |
Ring | Worse | 15.8 (6) | 2.6 (1) | 0.108 |
Coin | Worse | 10.5 (4) | 7.9 (3) | 1.000 |
Behaviour | Worse | 26.3 (10) | 28.9 (11) | 1.000 |
Tone | Decreased | 34.2 (13) | 56.8 (21^) | 0.084 |