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Table 4 Proportion of children with worse performance on day 9, 10 and 14 compared to day 7, in children with P. falciparum treated with AS7 or MAS7.

From: The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria

   Day 9 - Day 7
Neurological Test Component Result compared to previous test AS7 N = 39 MAS7 N = 39 P*
Box Worse 17.9 (7) 20.5 (8) 1.000
Cube Worse 15.4 (6) 28.2 (11) 0.272
Ring Worse 12.8 (5) 20.5 (8) 0.545
Coin Worse 12.8 (5) 12.8 (5) 1.000
Behaviour Worse 33.3 (13) 30.8 (12) 1.000
Tone Decreased 46.2 (18) 53.8 (21^) 0.651
   Day 10 - Day 7
   AS7 N = 39 MAS7 N = 39 P*
Box Worse 12.8 (5) 15.4 (6) 1.000
Cube Worse 23.1 (9) 33.3 (13) 0.457
Ring Worse 5.1 (2) 20.5 (8) 0.087
Coin Worse 7.7 (3) 12.8 (5) 0.711
Behaviour Worse 25.6 (10) 30.8 (12) 0.802
Tone Decreased 38.5 (15) 50 (19^) 0.363
   Day 14 - Day 7
   AS7 N = 38 MAS7 N = 38 P*
Box Worse 15.8 (6) 21.1 (8) 0.768
Cube Worse 23.7 (9) 28.9 (11) 0.795
Ring Worse 15.8 (6) 2.6 (1) 0.108
Coin Worse 10.5 (4) 7.9 (3) 1.000
Behaviour Worse 26.3 (10) 28.9 (11) 1.000
Tone Decreased 34.2 (13) 56.8 (21^) 0.084
  1. *comparison of 2 × 2 for AS7 vs MAS7
  2. ^Tone 1 less than N for MAS7 on each comparison