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Table 5 Paired comparison of the time (median [min-max] seconds) to put coins into the coin box at each specified day

From: The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria

Days of comparison Time N pairs Controls (well, no fever)
    Earlier day Later day P*
0-7 6 coins 18 13.8 [11-32] 13.8 [11-27.5] 0.722
  12 coins 18 31.5 [23-94] 30 [23.5-55.5] 0.554
0-28 6 coins 15 14 [11-32] 14 [9-18] 0.172
  12 coins 14 32 [25-94] 29 [22-50] 0.158
7-9 6 coins n.a n.a n.a n.a
  12 coins n.a n.a n.a n.a
7-10 6 coins n.a n.a n.a n.a
  12 coins n.a n.a n.a n.a
7-14 6 coins 19 15.0 [10-48] 14.8 [11-39.5] 0.157
  12 coins 17 30.5 [23.5-55.5] 31.5 [23.5-69.0] 0.820
7-28 6 coins 17 14.5 [10.5-35.5] 13.5 [8.5-23.5] 0.055
  12 coins 16 29.5 [23.5-76] 29 [22-83] 0.510
    Malaria - AS7
0-7 6 coins 12 12.3 [10-26.5] 13.5 [10-35.5] 0.166
  12 coins 12 27.5 [22-68.5] 26.5 [22-58.5] 0.413
0-28 6 coins 10 13 [10-27] 13 [9-23] 0.673
  12 coins 9 28 [22-69] 28 [20-73] 0.260
7-9 6 coins 15 14.5 [10-35.5] 13.5 [7.5-31] 0.459
  12 coins 14 27.0 [21.0-58.5] 27.5 [20-69] 0.126
7-10 6 coins 16 15.3 [10-35.5] 16.8 [8.5-30.5] 0.529
  12 coins 14 32.0 [21.0-58.5] 33.5 [20-52.5] 0.700
7-14 6 coins 14 14.3 [10.5-35.5] 17.3 [8.0-28.5] 0.201
  12 coins 12 25.8 [21.0-58.5] 29.0 [19-78.0] 0.480
7-28 6 coins 13 14 [10.5-35.5] 14 [8.5-22.5] 0.059
  12 coins 11 25.0 [21.0-56.0] 28.0 [20-55.0] 0.722
    Malaria - MAS7
0-7 6 coins 18 15 [10-23] 14.5 [7-30.5] 0.604
  12 coins 18 32.3 [21-47.5] 29.8 [20-51] 0.066
0-28 6 coins 16 15 [10-23] 14 [6-26] 0.277
  12 coins 14 33 [21-48] 30 [20-62] 0.220
7-9 6 coins 20 15.8 [7-34.5] 13.8 [8-31] 0.067
  12 coins 19 33 [20-65.5] 30 [18-50] 0.040
7-10 6 coins 20 15.5 [7-34.5] 13.3 [8.5-26] 0.030
  12 coins 18 30.5 [20-52.5] 30.8 [18-67.5] 0.924
7-14 6 coins 19 15.5 [7-34.5] 14.5 [8.5-33.0] 0.573
  12 coins 17 31.0 [22.5-52.5] 31.0 [20.0-70] 0.135
7-28 6 coins 20 15.5 [7-34.5] 14.3 [6-28.5] 0.025
  12 coins 18 30.5 [20.-61.5] 30.0 [20-61.5] 0.316
  1. *P = Wilcoxon Signed Ranks Test for paired samples at specified days; N = number of pairs analysed