Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditions

Malaria Journal

Table 1 Adhesion of C24, A4, ItG and JDP8 pRBC per mm² to purified receptors and endothelial cells as shown by Gray et al., 2003.

	ICAM-1 (100 μg/ml)	CD36 (2 μg/ml)	HUVEC (ICAM-1)	HDMEC (ICAM-1, CD36)
C24	291 ± 85	2797 ± 740	19 ± 4	73 ± 14
A4	2082 ± 421	1655 ± 408	37 ± 2	707 ± 57
ItG	5615 ± 738	2589 ± 326	224 ± 12	1521 ± 124
JDP8	6701 ± 1148	407 ± 122	231 ± 23	1134 ± 65

This data describes the binding phenotypes of four laboratory isolates, used in the present study, when independently tested under static conditions. Static assays were carried out as described previously [4, 8]. Data shown is the mean number of pRBC per mm² ± standard error of the means of 3-5 experiments.

ISSN: 1475-2875