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Table 3 Genotypic patterns of P. falciparum isolates in pfmdr1, pfcrt, dhfr, and dhps genes in the wet and dry seasons

From: Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia

Type Genotypic Pattern* Frequency (isolates)
   Wet Season Dry Season
1. NNKAKASC (wild type) - 2
2. NN(K/T)AKASC 1 -
3. N(N/D)TAKASC 11 25
4. (N/Y)(N/D)TAKASC 3 12
5. NNTAKANR 2 2
6. N(N/D)TAKASR 2 -
7. Y(N/D)(K/T)AKA(S/N)R 1 -
8. YNTAKASC 19 6
9. YNTAKA(S/N)R 2 -
10. Y(N/D)TAKASC 15 1
11. NDTAKASC 17 19
12. (N/Y)NTAKANR 2 -
13. (N/Y)(N/D)KAKASC 5 -
14. (N/Y)(N/D)TAKA(S/N)R 3 -
15. N(N/D)(K/T)AKASC 1 -
16. NNTAKA(S/N)R 1 -
17. YNTAKANR 3 -
18. NDTAKANR 2 5
19. NNKAKANR 4 8
20. NNTAKASC 10 22
21. YNTGKASC - 2
22. Y(N/D)TAKASC 4 1
23. -D(K/T)AKA(S/N)C 1 -
24. -DTAKASC 14 21
25. -NTAKANR 2 3
26. -NKAKASC 3 -
27. -DKAKASC 2 4
28. -NTAKASC 2 5
29. -(N/D)TAKA(S/N)C 1 -
30. -(N/D)TAKASC 10 24
31. -(N/D)KAKASC 1 1
32. -DTAKA(S/N)C 2 2
3. (N/Y)(N/D)TAK--- 5 2
34. (N/Y)(N/D)KAK--- 5 2
35. (N/Y)(N/D)TAK--- 8 2
36. NDTAK--- 7 2
37. NNTAK--- 8 3
38. YNT----- 6 2
39. YNK----- 1 1
40. -(N/D)TAK--- 1 2
41. -DTAK--- 5 3
42. -(N/D)(K/T)----- 1 3
43. N-AK---- 2 2
44. ND------ 10 22
45. --T----- 8 20
  Total 213 231
  1. *1st letter = N86Y and 2nd letter = N1042D for pfmdr1 gene, 3rd letter = K76T for pfcrt gene, 4th letter = A437G and 5th letter = K540E for dhps gene, 6th letter = A16V, 7th letter = S108N/T and 8th letter = C59R for dhfr gene. Letters in parentheses indicate mixed allelic infection. -- indicates unsuccessful amplification.