Figure 4
Relationship between parameters of the mortality function and ookinete density fed. Linear functions (as illustrated in Equation (2)) are fitted to the relationship between the parameter values of the mortality function and parasite density fed to each group of mosquitoes (ookinetes per μl of blood). Shaded areas represent 95% confidence intervals. (A) Parameter ν, which predominantly represents the increase in mortality rate with time-post feeding; parameter values (and 95% confidence intervals), ν0 = 1.18 × 10-4 (4.65 × 10-5, 1.40 × 10-4)**, ν1 = 6.43 × 10-8 (4.29 × 10-8, 2.60 × 10-7)**. (B) Parameter δ, which predominantly represents the initial decline in mortality rate with time post-feeding; δ1 = -3.27 × 10-3 (-4.13 × 10-3, -1.31 × 10-3)**, δ1 = -1.30 × 10-6 (-6.77 × 10-6, -1.24 × 10-6)*. (C) Parameter θ, which represents the mortality rate at the time of feeding; θ0 = 3.09 × 10-2 (9.69 × 10-3, 5.06 × 10-2)**, θ1 = 1.07 × 10-5 (5.99 × 10-6, 5.33 × 10-5)*. Significant p-values (* represents a p-value < 0.05 and ** represents a p-value < 0.001) indicate that the best-fit mortality function includes each of the parameter values in Equation (2).