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Table 1 Summary statistics for cages of An. stephensi mosquitoes fed different estimated P. berghei ookinete densities

From: Anopheles mortality is both age- and Plasmodium-density dependent: implications for malaria transmission

Experiment (date) Estimated ookinete density fed (per μl) Mean number of oocysts per mosquito on day 10* (range) Mean sporozoite score per mosquito on day 22* Total number of mosquitoes in each cage Median survival (days) (95% C.I.)
1 0    442 32 (30, 34)
(August 2007) 100 46.4 (0-251) 2.4 399 ND (25, ND)
  400 141.8 (0-307) 3.0 645 26 (23, 31)
  2,000 259.6 (0-591) 3.7 562 21 (19, 24)
2 0    733 33 (32, 35)
(April 2008) 100 55.3 (0-212) 2.0 565 ND (ND, ND)
  400 83.1 (0-259) 2.6 662 34 (32, ND)
  2,000 138.4 (0-477) 1.8 502 30 (29, ND)
3 0    625 42 (41, ND)
(July 2008) 50 11.3 (0-47) 1.2 815 36 (35, 37)
  250 67.6 (0-121) 1.7 852 36 (34, 38)
  1,000 96.8 (0-200) 2.9 999 34 (32, 35)
  1. Arithmetic mean parasite load in 20, randomly chosen surviving mosquitoes.
  2. * Parasite densities presented from the dissections on days 10 and 22 as these are the standard days used in determining oocyst and salivary gland sporozoite density and therefore allow comparisons to be made with published studies, such as Sinden et al [47].
  3. Sporozoites counted using a scoring system; 0, 0 sporozoites; 1, 1 to 10 sporozoites; 2, 11 to 100 sporozoites; 3, 101 to 1,000 sporozoites; 4, 1,001 to 10,000 sporozoites; 5, over 10,000 sporozoites.
  4. ND, not determined as survival curve does not cross 0.5 and therefore the median survival cannot be calculated.