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Table 1 Pharmacokinetic parameters of sulphadoxine in a patient with falciparum malaria treated with a single standard oral dose of sulphadoxine-pyrimethamine tablet.

From: A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies

Parameter

 

T 1/2 (day)

3.50

Cmax (μg/ml)

212.02

AUC0-28 (μg/ml.day)

884.84

  1. AUC0-28: Area under the blood concentration-time curve from time 0 to day 28
  2. Cmax: Peak blood concentration
  3. T1/2: Elimination half life