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Table 2 APC absolute numbers and immunophenotype in cord blood samples.

From: Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells

  APC subset
Parameter: median (± interquartile) Monocytes MDC   PDC
  CD14 + BDCA-1 + BDCA-3 + BDCA-2 +
% of total CBMC 13.00 ± (7.10) 0.62 ± (0.42) 0.19 ± (0.18) 0.25 ± (0.18)
absolute no./ml 624,787 ± (571,630) 23,850 ± (30,430) 8,160 ± (12,225) 9,680 ± (9,032)
% HLA-DR+ cells 93.87 ± (7.09) 93.53 ± (11.01) 59.95 ± (28.55) 82.64 ± (31.69)
HLA-DR, MFIa 132.71 ± (17.69) 162.50 ± (18.81) 118.26 ± (40.81) 129.9 ± (39.59)
% CD86+ cells 50.28 ± (34.37) 44.67 ± (22.15) 35.95 ± (20.98) 18.47 ± (13.41)
CD86, MFI 62.36 ± (30.17) 57.51 ± (21.12) 45.54 ± (17.80) 33.29 ± (13.77)
  1. Immunophenotyping was performed on 55 cord blood samples; 27 from malaria infected women and 28 from uninfected women. APC were quantified as a percentage of the total CBMC. Absolute numbers of MDC, PDC and monocytes were calculated from CBMC counts. HLA-DR and CD86 expression levels were then examined in different APC subsets.
  2. a; MFI, mean fluorescence intensity