Table 3 Immunophenotype of fetal APC upon TLR and Hz stimulation.
Monocytes | MDC | ||||||
|---|---|---|---|---|---|---|---|
Parameter median (± interquartile) | stimulus | Total CB | MP-Negative | MP-Positive | Total CB | MP -Negative | MP-Positive |
% HLA-DR+ cells | unstimulated | 89.34 ± (13.90) | 89.33 ± (16.57) | 89.79 ± (7.27) | 88.78 ± (19.83) | 87.33.40 ± (19.83) | 92.62 ± (20.13) |
Hz | 91.03 ± (10.10) | 90.46 ± (11.97) | 92.27 ± (8.31) | 90.99 ± (12.22) | 89.40 ± (13.55) | 91.37 ± (7.88) | |
LPS | 96.73 ± (6.22) | 96.73 ± (7.61) | 96.45 ± (3.14) | 93.24 ± (11.08) | 93.24 ± (11.66) | 93.38 ± (15.23) | |
Poly I:C | 96.79 ± (4.68) | 96.79 ± (7.99) | 96.70 ± (2.27) | 93.99 ± (12.57) | 93.08 ± (9.54) | 92.09 ± (16.42) | |
HLA-DR, MFIa | unstimulated | 120.81 ± (20.14) | 121.15 ± (24.36) | 119.54 ± (16.48) | 143.85 ± (23.19) | 143.57 ± (21.28) | 149.29 ± (22.77) |
Hz | 122.08 ± (20.42) * | 125.36 ± (23.00) | 121.47 ± (15.15) | 146.96 ± (14.93) | 151.30 ± (14.69) | 156.06 ± (20.47) | |
LPS | 135.72 ± (16.78)* | 137.56 ± (18.02) | 133.23 ± (13.82) | 152.40 ± (16.28)* | 145.49 ± (19.31) | 150.67 ± (13.84) | |
Poly I:C | 136.53 ± (15.66)* | 137.27 ± (19.29) | 136.41 ± (13.51) | 150.16 ± (14.93)* | 150.61 ± (16.72) | 149.60 ± (16.35) |