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Table 4 Accumulation of MP in placenta does not affect IL-12 production by APC upon TLR3 and TLR4 stimulation.

From: Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells

  

Monocytes

 

MDC

 

Parameter

median (± interquartile)

stimulus

MP-Negative

MP-Positive

MP-Negative

MP-Positive

IL-12 (% positive cells)

LPS

3.55 ± (4.13)

2.70 ± (3.15)

3.13 ± (3.72)

2.13 ± (1.72)

 

Poly:IC

2.33 ± (3.37)

3.99 ± (4.49)

1.95 ± (4.01)

2.38 ± (3.09)

  1. Intracytoplasmic IL-12 production by APC upon TLR3 and TLR4 stimulation was analysed on 43 cord blood samples; 31 from MP-negative women and 12 MP-positive women. All comparisons between MP-negative and MP-positive women were not significant.
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Malaria Journal

ISSN: 1475-2875

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