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Table 4 Accumulation of MP in placenta does not affect IL-12 production by APC upon TLR3 and TLR4 stimulation.

From: Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells

   Monocytes   MDC  
Parameter
median (± interquartile)
stimulus MP-Negative MP-Positive MP-Negative MP-Positive
IL-12 (% positive cells) LPS 3.55 ± (4.13) 2.70 ± (3.15) 3.13 ± (3.72) 2.13 ± (1.72)
  Poly:IC 2.33 ± (3.37) 3.99 ± (4.49) 1.95 ± (4.01) 2.38 ± (3.09)
  1. Intracytoplasmic IL-12 production by APC upon TLR3 and TLR4 stimulation was analysed on 43 cord blood samples; 31 from MP-negative women and 12 MP-positive women. All comparisons between MP-negative and MP-positive women were not significant.