Total numbers of malaria parasites in the body of two adults (logarithmic scale; vertical axis) who develop similar hyperparasitaemias are shown. The days since acquiring the infection are shown on the horizontal axis. The pre-erythrocytic development is approximately 6 days. On the left A; the parasite multiplication factor (PMF) per asexual cycle is 25 representing highly efficient multiplication. On the right B; the multiplication factor is 6 per cycle, so it takes longer to develop hyperparasitaemia.