Impaired everyday memory associated with encephalopathy of severe malaria: the role of seizures and hippocampal damage

Table 1 Univariate analysis of health factors and seizure variables on impaired everyday memory of children

Variable	P-value	OR associated with impairment	95% CI
Sex (female)	0.125	1.803	0.850 to 3.826
Age
7 years	0.652	0.791	0.285 to 2.193
8 years	0.836	0.897	0.323 to 2.494
9 years	0.902	1.062	0.407 to 2.771
Diagnosis
Cerebral malaria	0.003	4.675	1.692 to 12.913
Malaria plus seizures	0.184	2.131	0.699 to 6.498
Nutrition
weight for age	< 0.001	5.434	2.373 to 12.445
Height for weight	< 0.001	4.861	2.249 to 10.507
SES (high)	0.235	0.618	0.280 to 1.367
Schooling	< 0.001	0.154	0.062 to 0.381
Cognitive language (IQ proxy)*	< 0.001	26.444	0.781 to 0.919
Epilepsy	0.438	0.549	0.121 to 2.501
Seizure duration (at least 5 min)	0.040	2.829	1.049 to 7.626
Seizure duration (5> × >30 min)	0.936	0.957	0.324 to 2.821
Seizure duration (more than 30 min)	0.037	2.870	1.064 to 7.740
Multiple seizures (less than 3)	0.557	1.373	0.477 to 3.948
Multiple seizures (between 4 and 9)	0.246	2.063	0.607 to 7.012
Multiple seizures (more than 9)	0.008	4.012	1.426 to 11.291

*Cognitive language scores were used as a proxy for IQ. Age was compared to children aged 6 years old and diagnosis compared to unexposed children

ISSN: 1475-2875