Table 1 Clinical Laboratory findings

Haemoglobin (mmol/l)

7.3 - 9.7

Leukocytes (*10⁹/l)

3.5 - 11.0

Platelets (*10⁹/l)

120 - 350

Glucose (mmol/l)

4.0 - 5.5 (fasting)

Sodium (mmol/l)

137 - 144

Potassium (mmol/l)

3.4 - 4.6

Creatinin (umol/l)

45 - 90

Urea nitrogen (mmol/l)

3.0 - 7.0

Bilirubin (umol/l)

≤ 17

Alkaline phosphatase (U/l)

≤ 120

Aspartate aminotransferase (U/l)

≤ 40

Alanine aminotransferase (U/l)

≤ 45

Lactate dehydrogenase (U/l)

≤ 450

gamma GT (U/l)

≤ 35

Creatinin Kinase (U/l)

≤ 170

Troponin I (ug/l)

≤ 0.20

CRP (mg/l)

≤ 10

Cholesterol (mmol/l)

4.7 - 6.5

Triglycerides (mmol/l)

0.8 - 2.0

HDL cholesterol (mmol/l)

1.10 - 1.70

LDL cholesterol (mmol/l)

≤ 3.5

Coagulation assays

INR

0.9-1.1

Fibrinogen (mg/l)

2000-4000

Factor VIII activity (%)

60-150

Protein C activity (%)

70-150

Free protein S antigen (%)

55-115

Homocystein (μmol/l)

< 13.4

Antithrombin III (%)

85-120

Factor II mutation

negative

Factor V (Leiden) mutation

negative

von Willebrand Factor (%)

50-150

ADAMTS13 activity (%)

60-140

Additional tests

Convalescent microbiological tests

adenovirus, RS-virus, influenza virus, mycoplasma pneumonia, Chlamydia, Q-fever, para-influenza, enterovirus

Auto-immune antibodies

ANCA, anticardiolipin antibodies, β2 glycoprotein, lupus anticoagulans, anti-heart (rat) antibodies

Toxicology test

tetrahydrocannabinol, amphetamine-derivatives, cocaine, diazepam, methadone, tramadol, opiates

Inflammatory parameters

Interleukin 6, Interleukin 8

Time after last dose

Artemether

Dihydroartemisinin

Lumefantrine

Desbutyl-lumefantrine