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Table 1 Characteristics of complicated and uncomplicated malaria patients

From: IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

Characteristics

Complicated

malaria (110)a

Uncomplicated

malaria (169)a

P-valueb

Agec(range)

25.0 (14-67)

24.0 (13-65)

0.849

Sex (male/female)

75/35

133/36

0.137

Nationalityd

   

   Burmese

17 (15.5)

24 (14.2)

0.614

   Karen

18 (16.4)

27 (16.0)

 

   Mon

37 (33.6)

72 (42.6)

 

   Thai

38 (34.5)

45 (26.6)

 

   Laos

0

1 (0.6)

 

Blood groupsd

   

   A

21 (19.1)

27 (16.0)

0.556

   AB

6 (5.5)

7 (4.1)

 

   B

34 (30.9)

58 (34.3)

 

   O

47 (42.7)

66 (39.1)

 

   NR

2 (1.8)

11 (6.5)

 

Haemoglobin variants*d

   

   Hb variants

14 (12.7)

29 (17.2)

0.825

   Normal

95 (86.4)

133 (78.7)

 

   NR

1 (0.9)

7 (4.1)

 

G6PD deficiencyd

   

   Deficiency

13 (11.8)

14 (8.3)

0.597

   Normal

96 (87.3)

153 (90.5)

 

   NR

1 (0.9)

2 (1.2)

 

Parasitaemiae (range)

117 322 (33-1 336 900)

5641 (17-238 800)

<0.0001

Highest fever°Cf

38.1 ± 1.005

38.4 ± 0.981

0.011

Haemoglobin g/df

11.4 ± 0.24

12.1 ± 0.17

0.021

Creatinine mg/dlf

1.36 ± 1.21

0.88 ± 0.37

<0.0001

Glucose nmol/lf

131.47 ± 62.06

118.17 ± 28.78

0.016

Splenomegalyg

   

   Positive

18 (16.4)

3 (1.8)

0.039

   Negative

92 (83.4)

166 (98.2)

 

Hepatomegalyg

   

   Positive

66 (60)

32 (18.9)

< 0.0001

   Negative

44 (40)

137 (81.1)

 

Previous malaria episodesd

   

   Yes

30 (27.3)

93 (55.0)

< 0.0004

   No

78 (70.9)

76 (45)

 

   NR

2 (1.8)

0

 
  1. a = Number of patients, b = Mann Whitney U or unpaired t test used for the analysis, c = Median, d = Percentages (in the parenthesis), e = Geometric mean/ml of blood, f = Mean ± SD, g = Percentages of individual with enlarged spleens and/or liver are in the parenthesis. *The Hemoglobin (Hb) variants includes HbE, HbF. NR = No report.