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Table 4 Anti-P. falciparum IgG1 and IgG3 levels (median) according to IL4-590 genotypes in complicated malaria patients with or without previous malaria experiences.

From: IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

 

CM

CC (5)a

CT (46)a

TT (53)a

P -value#

Anti-Pf IgG1*

-

24.12

18.04

0.628

 

223.80

-

18.04

0.025

 

223.80

24.12

-

0.037

Anti-Pf IgG3*

-

1.20

0.51

0.030

 

1.51

-

0.51

0.159

 

1.51

1.20

-

0.455

  

CME

  
 

CC (2)

CT (11)

TT (14)

P-value

Anti-Pf IgG1*

-

31.13

53.04

0.983

 

280.43

-

 

0.835

 

280.43

31.13

53.04

0.830

Anti-Pf IgG3*

-

5.62

1.32

0.075

 

8.06

-

1.32

0.384

 

8.06

5.62

-

0.961

  

CMN

  
 

CC (3)

CT (33)

TT (38)

P-value

Anti-Pf IgG1*

-

13.94

8.54

0.636

 

223.80

-

8.54

0.002

 

223.80

13.94

-

0.004

Anti-Pf IgG3*

-

0.80

0.40

0.217

 

1.51

-

0.40

0.154

 

1.51

0.80

-

0.274

  1. * = μg/ml, #Statistical analysis of differences in IgG subclass levels
  2. between the different genotypes tested with unpaired t-test,
  3. a = Number of patients (in the parenthesis).
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Malaria Journal

ISSN: 1475-2875

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