Table 3 Contraindication (and complicating drugs) to halofantrine in 5 children with fatal outcome of cardiac origin presumably related to halofantrine
From: Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base
patient #3 (13 y. old) | known history of cardiomyopathy (treated by furosemide) |
|---|---|
patient #10 (2 y. old) | severe anaemia, dehydration (+ amodiaquine prior to halofantrine) |
patient #15 (11 y. old) | known history of cardiopathy with cardiac arrhythmia (+chloroquine and amodiaquine prior to halofantrine) |
patient #21 (8 y. old) | severe/cerebral malaria + bradycardia (+ potassium injection) |
patient #32 (12 y. old) | HF overdosing (45 mg/kg) (+ concomitant norfloxacine + possible intake of amodiaquine) |