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Table 1 Demographic data and immediate therapeutic response of children with P falciparum gametocytaemia treated with mefloquine or artesunate-mefloquine

From: Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children

  Values* for the following treatment groups P. value
Parameter Artesunate-Mefloquine Mefloquine All  
No. of patients 44 64 108 -
Male/Female 22/22 32/32 54/54 -
Age (year) 6.1 ± 3.1 6.9 ± 2.8 6.5 ± 2.9 0.18
  1-13 0.8-13 0.8-13  
No. < 5 years 14 12 26  
Weight (kg) 18.2 ± 7.1 19.4 ± 5.6 18.9 ± 6.3 0.31
  8-46 7-33 7-46  
Height (cm) 109.2 ± 19.4 115.2 ± 16.1 112.7 ± 17.7 0.09
  65-141 74-147 65-147  
Duration of illness (d) 2.5 ± 0.9 3.1 ± 1.4 2.9 ± 1.3 0.01
  1-5 1-7 1-7  
Body temperature (°C) 38.3 ± 1.2 38.2 ± 1.2 38.2 ± 1.2 0.6
  36.2-40.5 35.2-40.5 35.2-40.8  
Parasite count (/μL)     
   Geometric mean 29280 27760 28590 0.9
   Range 2200-884571 2400-520000 2200-884571  
Gametocyte density (/μL)     
   Geometric mean 18 28 23 0.24
   Range 6-216 6-468 6-468  
Fever clearance time (d)     
  1.3 ± 0.6 (n = 30) 1.3 ± 0.8 (n = 40) 1.3 ± 0.7 0.86
  1-3 1-5 1-5  
Parasite clearance time (d)     
  1.4 ± 0.5 1.9 ± 0.8 1.7 ± 0.8 0.003
  1-3 1-4 1-4  
  1. Data are shown as mean ± SD or median (range),