Design and pre-clinical profiling of a Plasmodium falciparum MSP-3 derived component for a multi-valent virosomal malaria vaccine

Table 1 Cross-reactivity of anti FB-12 mAbs with FB-12-derived peptides in ELISA and with P. falciparum blood-stage parasites in IFA and Western blotting (WB) analysis.

mAb	full length peptides				truncated peptides			Schizont
	FB-12	FB-13	FB-14	FB-16	FB-II-57	FB-I-171	FB-I-107
	211-237	211-237	211-237	211-237	227-237	222-237	211-228	IFA	WB
DV2.2 (IgG₁/k)	+	+	+	+	-	-	+	+	+
DV3.1 (IgG₁/l)	+	+	+	+	-	+	+	+	+
DV3.2 (IgG₁/l)	+	+	+	+	-	-	+	+	+
DV3.3 (IgG₁/l)	+	+	+	+	-	+	+	+	-
DV3.4 (IgG_2b/l)	+	+	+	+	-	+	+	+	+

ISSN: 1475-2875