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Table 1 Relative frequencies of polymorphic Pfrct gene SNPs according to villages, ages and years

From: Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger

  Number of samples Overall Banizoumbou vs Zindarou Adults vs under 15 2003 vs 2006
pfcrtMet74IIe 87 10.3% 11.1% vs 9.5%
(p = 1.0)
22.2% vs 7.1%
(p = 0.084)
0.0% vs 21.4%
(p = 0.001)*
pfcrtLys76Thr 318 32.4% 38.3%vs 25.2%
(p = 0.013)*
37.8% vs 31.5%
(p = 0.405)
20.0% vs 44.4%
(p = 0.013) *
pfcrtHis97gln 87 11.5% 15.6% vs 7.1%
(p = 0.317)
16.7% vs 10.1%
(p = 0.425)
2.2% vs 21.4%
(p = 0.006)
pfcrtAla220Ser 77 10.4% 10.0% vs 10.8%
(p = 1.0)
25.0% vs 6.5%
(p = 0.053)
0.0% vs 19.5%
(p = 0.006)*
  1. in bold p < 0.05
  2. * link kept in logistical regression model)
  3. Global trend for samples from 2003 to 2006 years for pfcrt76 SNP gene