Skip to main content

Table 4 Relative frequencies of polymorphic Pfmdr and pfATPase genes SNPs according to villages, ages and years

From: Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger

 

Number of samples

Overall

Banizoumbou vs Zindarou

Adults vs under 15

2003 vs 2006

pfmdrAsn86Ser

86

17.4%

13.6% vs 21.4%

(p = 0.341)

5.9% vs 20.3%

(p = 0.284)

22.7% vs 11.9%

(p = 0.186)

pfmdrSer1034Cys

86

4.6%

6.7% vs 2.4%

(p = 0.618)

12.5% vs 2.9%

(p = 0.156)

0.0% vs 9.8%

(p = 0.048)*

pfATPaseAla623Glu

86

4.7%

6.8% vs 2.4%

(p = 0.616)

5.6% vs 4.4%

(p = 1.0)

0.0% vs 9.5%

(p = 0.053)

  1. in bold p < 0.05
  2. * link kept in logistical regression model