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Table 2 Individual dhfr and dhps mutations by treatment and treatment outcome

From: Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa

  Total SP SP Total SP-AS SP-AS Total
  Treatment success Treatment failure   Treatment success Treatment failure  
N = 38# N = 24# N = 14 N = 27* N = 23* N = 4 N = 65#*
dhfr n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Arg-59
Wild 1 (2.8) 1 (4.5) 0 (0) 3 (11.5) 2 (9.1) 1 (25) 4 (6.5)
Mutant 25 (69.4) 16 (72.7) 9 (64.3) 18 (69.2) 15 (68.2) 3 (75) 43 (69.4)
Mixed 10 (27.8) 5 (22.7) 5 (35.7) 5 (19.2) 5 (22.7) 0 (0) 15 (24.2)
dhps
Gly-437
Wild 4 (11.1) 2 (9.1) 2 (14.3) 1 (3.8) 1(4.5) 0 (0) 5 (8.1)
Mutant 30 (83.3) 19 (86.4) 11 (78.6) 24 (92.3) 20 (90.9) 4 (100) 54 (87.1)
Mixed 2 (5.6) 1 (4.5) 1 (7.1) 1 (3.8) 1(4.5) 0 (0) 3 (4.8)
Glu-540
Wild 33 (91.7) 21 (95.5) 12 (85.7) 26 (100) 22 (100) 4 (100) 59 (95.2)
Mutant 3 (8.3) 1 (4.5) 2 (14.3) 0 (0) 0 (0) 0 (0) 3 (4.8)
Mixed 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
  1. # 1 not amplified and 1 not interpretable; *1 not amplified