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Table 1 Description of clinical surveillance sites and the characteristics of the catchment populations in relation to transmission intensity (Pf PR2–10-Plasmodium falciparum parasite prevalence in children 2 to 10 years).

From: Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity

Study Site

[Map Reference]

Dates

(years)

Malaria admissions

BCS1 ≤ 2 recorded

(Y/N)

SMA2 recorded

(Y/N)

Pf PR 2–10

(years recorded) [number examined]

Kilifi North, Kenya [A]

2004–07

(4)

712

Y

Y

1.3

(2005–07) [828]

Hodeidah, Yemen [B]

2002–04

(1.75)

283

Y

Y

1.7

(2005–06) [5886]

Bakau, The Gambia [C]

1992–94

(3)

99

Y

N

2.1

(1988) [386]3

Taiz, Yemen [D]

2002–04

(1.75)

1049

Y

Y

5.7

(2005–06) [4908]

Kilimanjaro, Tanzania [E]

2002–03

(1)

162

Y

Y

6.2

(2001–02) [382]

Humera, Ethiopia [F]

1994–95

(1)

458

N

Y

12.6

(1995) [616]

Kabale, Uganda [G]

2002–03

(1.5)

160

Y5

Y

18.0

(2006) [64]4

Kilifi South Junju, Kenya [A]

2005–07

(3)

92

Y

Y

25.9

(2005–07) [1601]

Mponda, Malawi [H]

1994–95

(1)

356

Y

Y

33.0

(1996)

Foni Kansala, The Gambia [I]

1994–95

(2)

193

Y

Y

34.1

(1991–92) [117]

Korogwe, Tanzania [J]

2002–03

(1)

3948

Y

Y

34.9

(2000–02) [927]

Sukuta, The Gambia [C]

1992–95

(4)

605

Y

N

42.4

(1996) [125]

Kilifi South Chonyi, Kenya [A]

1999–01

(3)

346

N

Y

43.0

(1999–01) [1918]

Kilifi North, Kenya [A]

1990–95

(5)

1358

Y

Y

51.9

(1995) [540]

Siaya, Kenya [K]

1992–96

(3)

715

Y

Y

75.1

(1995) [570]

Kilifi South, Kenya [A]

1992–96

(4)

766

Y

Y

76.9

(1996) [212]

Namawala/Michenga, Tanzania [L]

1991–92

(1)

144

Y

Y

87.5

(1989–91) [3947]

  1. 1BCS – Blantyre Coma Score
  2. 2 SMA Severe Malaria Anaemia defined as Hb <5 gm/dl or PCV<15%
  3. 3 The estimate of Pf PR was not temporally matched however it was regarded as a legitimate estimate for this peri-urban community four years later when the clinical surveillance data began.
  4. 4 Kabale is a high altitude area and while there were 3 years difference in the estimation of Pf PR and the clinical surveillance period the estimate of infection prevalence is regarded as a good approximation.
  5. 5 The investigators used a BCS ≤ 2 to describe cerebral malaria in children aged less than 5 years old and a Glasgow Coma score [32] of ≤ 8 for children 5–9 years.